Re: Bhatti et al.: Microcystic macular edema in optic nerve glioma (Ophthalmology. 2020;127:930)

Bhatti et al1Bhatti M.T. Mansukhani S.A. Chen J.J. Microcystic macular edema in optic nerve glioma.Ophthalmology. 2020; 127: 930Abstract Full Text PDF PubMed Scopus (2) Google Scholar present images from a patient with inner nuclear layer cysts visible on OCT the setting of an glioma.1Bhatti They attribute these to effect vitreous traction Müller cell footplates (forming limiting membrane) after degeneration ganglion cells and retinal fiber (RNFL). This is one hypothesis, but it should be noted that another mechanism postulated literature represent retrograde trans-synaptic (presumably bipolar cells) loss cells.2Lujan B.J. Horton J.C. Microcysts atrophy are caused by combined surface.Brain. 2013; 136e260Crossref (33) Scholar,3Abegg M. Dysli Wolf S. al.Microcystic edema: maculopathy neuropathy.Ophthalmology. 2014; 121: 142-149Abstract (90) It possible both mechanisms contributory.2Lujan We have reported previously patients visual associated silicone oil (after detachment surgery) exhibit RNFL cells, also demonstrate same microcystic change some years.4Shalchi Z. Mahroo O.A. Shunmugam al.Spectral domain optical coherence tomography findings long-term oil-related loss.Retina. 2015; 35: 555-563Crossref (29) The hypothesis less likely because they lack vitreous, although remains tractional element exists. plausible, has been demonstrated at other levels pathway, such as thinning secondary occipital cortex lesions.5Jindahra P. Petrie A. Plant G.T. Retrograde identified tomography.Brain. 2009; 132: 628-634Crossref (165) agree al term “microcystic edema” misnomer we prefer “retrograde maculopathy,”3Abegg which neutral precise mechanism, emphasizes primary role loss. Macular Edema Optic Nerve GliomaOphthalmologyVol. 127Issue 7PreviewA 42-year-old woman neurofibromatosis 1 bilateral (left larger than right) gliomas was seen for annual ophthalmic examination. Visual acuity 20/20 right eye 20/25 left relative afferent pupillary defect. hyporeflective lesions retina termed edema”; however, this misnomer. changes cystic spaces resulting preventing collapsing any neuropathy. Full-Text